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SNRI + Remeron question

Posted by bissie66 on June 7, 2008, at 10:36:04

Otherwise known as California Rocket Fuel. It's good stuff! The problem for me is, it poops out after 2-3 months, but then if I take a break of a month or so, it works again. It seems to be the Remeron that poops out, because in the past I would keep the Effexor on board and discontinue the Remeron temporarily. I've done this about 4 times, then my pdoc prescribed Cymbalta, which had no effect at all alone (for about 6-8 weeks), but when Remeron was added the magic happened. AFter 3 months the poop-out happened again. My pdoc just switched me to Pristiq which I've been on for about 5 days with no effect. My question: he says the Remeron + Pristiq can work but I think the Remeron has pooped out (so I stopped taking it temporarily). Do you think it's possible that by switching the SNRI, the combo will be effective again, without taking the Remeron holiday, i.e. the Prisiq will somehow kick the Remeron into effectiveness again? Doesn't make sense to me but why would the pdoc think it would work.


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