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Re: Day 6 on clozapine - Philippa + Experts » Jeroen

Posted by yxibow on June 6, 2008, at 4:19:25

In reply to Day 6 on clozapine - Philippa + Experts, posted by Jeroen on June 5, 2008, at 14:31:10

> hi, day 6 now,
>
> side effects are these:
>
> increased sweating, decreased appetite (strange isnt it) really, sedation high, sleep is normal from bedtime to morning so far so good no acrunylosis (wrong spelled) the decrease white blood dangerous side effect ,
> i ment mouth water
> also
>
> also when sleeping i have my spit inside my mouth when i wake up i have to swallow my
>
> effect on TD, i think its lesser but i wont anything false miraculous that's over now :p
>
>
> does anyone know how to know its that side effect? --> philippa what med are you on ?
>
> i hope laughopine RX :P

WBC -- White Blood Count, a threshold level of how many disease fighting (white blood cells) cells you have in your body.

Decreased appetite has been reported in post marketing.

Sweating has been reported in some larger studies at 6% in general

One study mentioned salivary hypersecretion (drooling) at 48% to Zyprexa at 6%.

Another larger study mentioned it in general at 31%

That's why you wake up and feel the need to spit. Its not the only agent that can cause this I believe but it is by far the most known.

Similarly, somnolence (drowsiness) at 48% to 25%.

Typically around 50% of people on clozapine mention some form of drowsiness, it is by far the largest side effect, followed by drooling, and risk of seizure cumulative up to 5% per year mainly based on dose -- this is the other thing monitored mainly for clozaril, not to scare you, but that is one of the two main medically concerning issues besides WBC.

http://www.nami.org/Template.cfm?Section=About_Medications&template=/ContentManagement/ContentDisplay.cfm&ContentID=8176

 

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