Posted by ace on May 28, 2008, at 0:33:03
In reply to Re: Clonidine Contributing to Depression? » ace, posted by SLS on May 26, 2008, at 5:58:08
> > > It's not too tough to do a Google search. Clonidine is depressogenic.
> > >
> > > http://www.google.com/search?hl=en&q=clonidine+AND+%28depressogenic+OR+depressive+OR+depression%29&btnG=Search
> > >
> > >
> > > - Scott
> >
> > I don't think we can say that as a 'blanket' claim.
>
> If by that, you mean that my claim is that clonidine produces depression 100% of the time, this is certainly not the case. However, the rate is high enough to consider it as a possibility any time this drug is used.
I did interpret your claim in such a way- I would agree with your statement here- that the rate is high enough to consider it a possibility- I personally just don't like to discount any drug as a possible treatment, especially when dealing with refractory illness> > I have seen in some that Clonide has indeed reduced depression.
>
> What was the case profile of these folks. Does anything stick out in your mind as a commonality among individuals with depression whom respond favorably to clonidine?Very much so- the vast majority were diagnosed with ADHD or ADHD type symptoms. Although I have seen anecdotes on 'normal' depression (without co-morbidity) responding to it favourably. I believe I have some on trials on it too- for OCD, ADHD- always with depression as a co-morbid problem.
>
> > You know as well as me the inprecision inherent in pyschopharmalogical treatment of the clinical psychiatric syndromes....
>
> Of course. However, I do not believe that inprecision is a de facto property of psychopharmacological treatment.At this point in time I would think it so. What would suggest otherwise to you at the present?
But it's not easy for psychiatry- how can such treatment be precise when we have no external evidence of any mental illness- there is only speculation and clinical opinion. I certainly not am suggesting that mental illness does not exist- I feel it does. However, I feel it is not analogous to most other biological diseases in that the aetiology in mental illness can not fit into a simple medical model. The same illness (i.e OCD) amongst a population of patients can have a totally different aetiologies in each patient- with perhaps, a common factor.We are close to producing tests for genotypes that will offer information that will help choose drugs for each individual.
>I have read somewhat about this- in particular with psychotic disorders. However, most studies end with the usual "more research needs to be done" With regards to OCD- have a look at this (if time permits)
http://www.medicalnewstoday.com/articles/40652.phpI certainly don't think the future is bleak. I think the time will come where psychiatry will be able to (in some form) conduct external validating test of pychopathology...
> How is school?
It's really good but demanding...I got through the GAMSAT here in NSW, so all is looking very good. However, I am a bit concerned about my own problems, and the fact that I take psychiatric drugs as possibly being of detriment to all...this issue is really making me anxious at the moment....
>
> - ScottCheers Scott- stay positive mate,
Andrew:)
>
poster:ace
thread:829199
URL: http://www.dr-bob.org/babble/20080519/msgs/831551.html