Posted by bleauberry on May 24, 2008, at 13:14:08
In reply to time of day of symptoms, posted by bissie66 on May 22, 2008, at 14:29:30
The pattern of cortisol fluctuation from the adrenal glands profoundly affects how the meds work, or don't work. During my last year on prozac+zprexa, and then replaced with lexapro and then zoloft, it was weird but I was a bit under the weather but basically ok in morning, took a rough dive in the afternoon, and then in the evening I felt absolutely perfectly fine. An adrenal stress index test, which shows the cortisol curve, matched my mood patterns exactly.
The adrenals are closely intertwined with thyroid also. So if you have thyroid issues, adrenal issues could be expected.
Unfortunately treating daily pattern hormonal imbalances is not well understood and tricky to do. Patients at Yahoo forums know the most about it, as far as I have seen.
You could take a look at the dosing times of your thyroid meds and tinker with those to see if the pattern can be manipulated. Change the time of day, take more frequent doses (but same total daily dose), and stuff like that. If hypothyroid, there could very well be hypoadrenal too. As one went bad first, the other followed in an attempt to maintain equilibrium. If there is hypoadrenalism, the two natural treatments are licorice root or adrenal cortex extract, sometimes both, but the real fix is 5mg-20mg daily of hydrocortisone.
poster:bleauberry
thread:830527
URL: http://www.dr-bob.org/babble/20080519/msgs/830888.html