Posted by ace on May 8, 2008, at 0:02:09
In reply to Re: Nardil- The best AD ever......., posted by simon79 on May 7, 2008, at 3:17:16
> Dear Ace
Hey- I felt a tad rude writing the quick message, so just back!
> I find your story so inspiring it almost brings tears to my eyes.
This is great! I hope that it did indeed lift your spirits.
I wish you all the very best in becoming a psychiatrist.Many thanks for this too!
> I myself have suffered from social anxiety (currently severe) and depression (currently moderate) for 14 years.When you say "severe" are you home-bound? What sort of symptoms do you get?
> After trying nurmerous drugs, a few emotional breakdowns, and abusing recreational drugs to escape my pain I have been given clonazepam and nardil.
In my opinion, this is a great combination.
My only query is my doc is titrating me up very slowly on the nardil, i'm currently on 30 and don't feel anything much from it or much in the way of side effects and he says "2 months and u will get full effect at that dose and then we can think about adding another 15mg"...
I disagree very strongly to what your doctor stated. Firstly, the titration regime is far too slow. The dose of 30mg will NOT, I feel strongly, produce any strong therapeutic effect regardless of time or any other variable. My sentiments are reinforced by your statement of having no side-effects, let alone therapeutic reaction.
Nardil typically has a slow onset, even at doses such as 60mg. The (rare) exceptions I have found are where people recieve an early response on a low dose, but then quickly need to higher the dose to retain benifits. I have seen this type of reaction to be rare.
MAOI's essentially have a lot of 'work' to do before they start to work therapeutically. Each person needs a certain amount of MAOI inhibition in order for the drug to have affect. I feel 30mg won't do this in the vast majority of cases!!
Also, certain metabolites of Nardil increase GABA levels, which, I feel plays a definite role in Nardil's effect.
All I am saying here is it takes time and the correct dose. I think your MD is correct about the time part, but he is way off about the dose.
MAOI's and, especially, TCA's are usually prescribed at TOO LOWER DOSES!!! And SSRI's far too high!
I have seen 1000's of anectodes on Nardil and read literally any and all clinical trials on it I could find.
I really feel your MD has not got the correct information on MAOI's. Is he/she a younger doctor?
I feel you should start of with 15mg bid, and increase by 15mg, every 3/5'th day until one reaches a maximum of 60mg (I recommend divided doses) This assumes one can tolerate any s/effects.
Once at 60mg, stay at this dose for a minimum of 6 weeks. If no response, increase to 90mg for a further 6 weeks. However, I feel that 60mg is the optimum dose where Nardil kicks in for most- 90mg has the potential to augment a wonderful AD/anti social phobic etc etc etc effectso it's gonna be a long time to get to 60...
I would politely talk to your doctor about this issue. I personally would ignore him/her, but that's just me, ha ha!
and god forbid i don't know what i would do if this drug doesn't work for meI would try to curtail those thoughts. For some reason I knew Nardil was going to work for me....I justknew it. Even when their was great doubt....I kept hope. Please do the same!!!!
Look at the psycho Babble history of Nardil responders and this will help!!! Their used to actually be some Nardil group ages ago, where these people who were in love with Nardil used to just post!
:(.. anyways.. do u think this is titrating up a bit too slowly?I think you know my answer=- WAY too slow!!!
i'm not sure whether to trust him or put my foot down and say i'm only waiting a month for each 15mg until i get to 60Even this is too slow!!!
Be polite to him. I can dig out some old studies that you can refer him too if you want??
Just remember that you are paying him for a service!
if i'm not hving any problems with side effects.
> Anyways sorry to hijack your thread with my problems :)Hey- no probs at all! Your 'hijack' is a welcome one! Sometimes I just have time factor problems....We are all so buzy in this world!!!
Your story was hugely inspirational for me and I'm sure many other people who are suffering.Thank you so much for this....this is my main purpose, and to feel I have achieved it, is such a great feeling. Please keep me up to date...!
Good luck with your studies i'm sure you will pass with flying colours!
Cheers!!!
God Bless!
Andrew
>
poster:ace
thread:827439
URL: http://www.dr-bob.org/babble/20080430/msgs/827872.html