Posted by Quintal on April 21, 2008, at 6:15:11
In reply to Re: Trying to coose an AD. Anyone tried lofepramine?, posted by undopaminergic on April 20, 2008, at 22:49:12
>You already have amisulpride. Take it 30-60 min. before you want to get up. If that's insufficient, add methylphenidate, and if that's insufficient switch to dextroamphetamine. Perhaps even modafinil would help, but I think it helps less with motivation and it brings greater risks of insomnia than the others.
Amisulpride doesn't do much of anything any more, but I could try taking it in bed to see if that helps. I just took a dose this morning and I can't tell I've taken anything. Stimulants are very much restricted in the UK, and I can't see anyone prescribing them on the NHS, much less my psychiatrist. When I was in hospital he told me to stay away from stimulants, even MAOIs (which he considers stimulating). I tried adrafinil and it just made me spaced out and gave me brain fog. I have no trouble staying awake druing the day, so I doubt modafinil would be of that much use. I did ask for it years ago, but the pdoc refused "I'm not prescribing any kind of stimulant".
>I recall that you can't get benzos. How about picamilon, phenibut or theanine (L-theanine)? Of these, I've only tried theanine, and found it to be a potent GABAergic agent at 1-2 grams. These are all pretty cheap if you buy them as powders.
I tried picamilon a few times, but it didn't seem to have any effect. I've never tried phenibut, but I've heard tolerance develops rapidly. L-theanine didn't seem to do a great deal either, but I was taking benzos at the time.
>How about morphine, plus memantine to prevent tolerance? Or maybe just codeine or tramadol?
Morphine would probably help, but again, nobody is going to prescribe such a drug on the NHS. I think the NICE guidelines have advised that memantine is less suitable for prescribing because of the high cost. I'm already addicted to OTC codeine products, and have been for years. I've developed tolerance to them. Tramadol was very effective, but only for a short while until tolerance set in. I read an artricle once where lamotrigine had also been shown to prevent opioid tolerance.
>Selegiline may be an alternative to the stimulants.
I think I still have a a few boxes of it somewhere. It just made me feel wired and irritable. Parnate would probably be the only realistic alternative to stims (and it did have a very powerful stimulant effect the last time I tried it).
Q
poster:Quintal
thread:824278
URL: http://www.dr-bob.org/babble/20080420/msgs/824541.html