Posted by SLS on April 19, 2008, at 15:13:16
In reply to Question For Scott, posted by bulldog2 on April 19, 2008, at 15:02:40
Hi Bulldog2.
This is conjecture:
> Currently doing deplin + Sam-e and getting a decent response thought not in remission.
Deplin can take 2-3 months to begin working. I think a brief "blip" response in the first week might indicate that things are heading in the right direction. Deplin produces an increase in S-AMe. Not only do I feel that the S-AMe is unecessary, it might even produce some dysphoria.
> Could I get by with a lower dose of Nardil such as 45 mg.
I would lower the dosage of Nardil only if you are having a difficult time tolerating side effects. I don't believe that you can lower an effective dosage of Nardil by adding Deplin.
> Also at lower doses is there less chance of a hypertensive crisis if I eat the wrong foods.
Sort of. The only thing is, this is probably at a dosage significantly lower than is necessary to maintain an antidepressant effect. In reality, it depends on the percentage of MAO being inhibited in the gut. I don't happen to know what the threshold is for reducing the tyramine reaction.
I apologize if I didn't get to your questions earlier.
- Scott
poster:SLS
thread:823248
URL: http://www.dr-bob.org/babble/20080412/msgs/824302.html