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Re: SSRI's vs. TCA's

Posted by undopaminergic on April 17, 2008, at 21:32:59

In reply to Re: SSRI's vs. TCA's, posted by cactus on April 15, 2008, at 16:14:56

>
> I also had amazing results from ropinirole, in regards to major mood elevation, (Dopamine agonist) but it made me really sick which I put up with for a while because I felt so good. It became too much in the end (vomitorium central). Tirate up very slowly, I did, but I still got quite ill.
>

You should have tried adding some amisulpride, sulpiride or perhaps even better, domperidone - a peripheral dopamine antagonist. All of these have the potential of largely eliminating such dopaminergic side effects as nausea and vomiting.

Personally, I did find pramipexole (a non-ergot dopamine agonist like ropinirole) to be highly mood-elevating, but that was very sporadic and unreliable, and after a couple or weeks or so, there were no positive effects at all.


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