Posted by undopaminergic on April 15, 2008, at 2:27:42
In reply to Re: Insomnia--drugs not working - a crazy idea, posted by Dopamine123 on April 13, 2008, at 21:48:59
> >Low dose of Remeron (like 7.5mg) has quite a sedative effect.
>
> Yeah remeronn can be very effective for helping a person get to sleep. It is both a 5-ht2a antagonist and histamine antagonist. Both of those actions improve sleep. I take it for sleep, and find it works pretty good. I've tried diphenhydramine and I hated that drug. It makes me feel really weird.
>Cyproheptadine is a H1/5-HT2-antagonist too - you may wish to try it for comparison. The adrenergic alpha2-antagonism of Remeron is probably detrimental to sleep, and may be the reason why Remeron is said to be less sedative at higher doses.
poster:undopaminergic
thread:822942
URL: http://www.dr-bob.org/babble/20080412/msgs/823381.html