Posted by Elizabeth Williams on March 1, 2008, at 19:54:22
I've been taking 30 mg of Parnate for more than two months for treatment-resistant atypical depression. At the 30 mg dose, the side effects are minimal. I had insomnia and myoclonic jerking, which went away after a few weeks. I also had afternoon fatigue, which has almost disappeared. I have lost over 25 pounds, which has been a great side effect. The problem is that I don't have any therapeutic effect. Every time I try to raise the dose past 30 mg, the postural hypotension is unbearable: severe fatigue, dizziness, sudden deafness and loud ringing in the ears. For the last couple of weeks, i have also been on 25 mcg Cytomel (t3) which has given me some more energy, but hasn't sigificantly improved the AD's therapeutic effect. Last week my Pdoc upped my Cytomel to 50mcg and upped my Parnate to 40 mg with the thought that maybe I could better tolerate the increase now that I've been on it for a while. Again, the hypotension is too much, and I am now doing the 50mcg Cytomel and 30 mg Parnate. Does anyone have any ideas that I could bring to my doctor regarding augmenting the Parnate so that I have some relief for my depression? I am feeling so disappointed because it seems that almost everyone on this site seems to have had good results from Parnate except for me. Please help!
poster:Elizabeth Williams
thread:815630
URL: http://www.dr-bob.org/babble/20080221/msgs/815630.html