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Re: ultram » Robert35

Posted by yxibow on February 24, 2008, at 0:05:37

In reply to Re: ultram, posted by Robert35 on February 22, 2008, at 4:15:12

> Hi yxibow,
>
> Thanks for your comment !
> Regarding serotonin syndrome: I have read there is only one absolute restriction in combinations with MAOI's ... .
> I discussed the possibility (prozac + tramadol) with the various doctors I have seen and a pharmacist but they think it is safe. One paindoctor said (what I don't understand bc as I understand SS can be lethal): if trouble arrises from this combo you can always go back to what you used before ... the damage is reversable .


Sub-clinical serotonin syndrome is not lethal, if noticed and reported by the patient or observed by a doctor. Lesser symptoms of SS will occur. I may have had that with some medication combination I forget. True serious SS is an immediate hospitalization and ICU issue.

>
> What do you mean by "that is also a concern in u(mu)-mediated forays by some doctors into fighting depression and pain"; what do mu receptors have to do with a serotonin syndrome ?

Nothing... mu receptors and others have to do with opiates. Pardon for the technical jargon mixup. I meant the same thing, experimenting with varieties of opiates for depressive and psychoneurological pain.

> Do you have (sorry I didn't read all of your posts) a good (combo of) drug(s) now ?
> Are you doing better ?
> (I am still struggling ..)

I'm sorry to hear that... yes we all struggle at times with biological disorders. I am having a difficult time at the moment -- and it isn't all about medication. Therapy is an important part of it because there is no magic pill that will erase my symptoms and not destroy me. I have a unique set of multi-diagnosis and polypharmacy.


My main agents that seem to work the best are Seroquel (for other purposes than pure psychosis) and long term Valium (which has been a problem reducing because it brings back symptoms -- also a sticky wicket because I reserve a possibility of trying Clozaril which means no Valium and more muscle/iatrogenic neurological things possibly exposed). I also take a mid amount of Luvox (I dont want to go up on it because I dont want more problems at the moment) and Lamictal which may possibly be doing something for mood, again a small dose. The Neurontin is hard to say, I think its merely an additive to the Valium but when it is removed things happen also yet there is some tolerance. The Robaxin is not psychiatric, particularly, though it is for another long term muscular iatrogenic issue with dumping a benzo years ago.


>
> Best wishes,
>
> Robert


-- thanks

Jay

 

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