Posted by yxibow on February 21, 2008, at 3:48:28
In reply to Seroquel question, posted by bissie66 on February 20, 2008, at 4:44:49
> Seroquel helps me a lot for anxiety and even for that kind of despair when I can't get out of bed but can't sleep bc I'm crying and my thoughts are so black there's no hope and no light at end of tunnel BUT when I take just a tiny amount (12.5 mg or less) it knocks me out - not good when I have to take care of my 5 year old. I have heard that a higher dose does not knock you out. My question - what dose is effective for anxiety but does not put you to sleep? Thanks.
Seroquel at any dose, trust me, can make one sedated because of the strong effects on the H1 (histamine) receptor. One can become somewhat used to this over time though this varies by the patient. It is somewhat dosal related though anyone fairly sensitive to activity at that receptor I would imagine could become sleepy at any dose.
I have been on it for some years and dropped it and started it recently for reasons I am not going to go into here but it doesn't really make me sleepy any more. It also works a bit differently, though it basically is an important agent at the moment for me.
I have driven on it in the far past at multiple split dosing if I can recall but I would not suggest that unless one can tolerate it. It is almost always given at bedtime for this reason and the consolidated dose is considered as good as multiple dosing as far as effectiveness regardless how short its half life is.
-- Jay
poster:yxibow
thread:813712
URL: http://www.dr-bob.org/babble/20080207/msgs/813872.html