Posted by Ron Hill on January 30, 2008, at 4:27:22
In reply to Deplin will not cause pernicious anemia, posted by Phillipa on January 27, 2008, at 12:25:25
Jan, et. al.
Jan, am I the one that has got you so confused on this issue? If so, I'm very sorry. That was certainly not my intent. You already get B12 shots, correct?
In any case, you are not going to get pernicious anaemia just by taking Deplin. All I've been trying to do is to alert people that are taking Deplin that they should also take methyl-B12. Patients taking L-methylfolate, or any other kind of folate, will somewhat reduce B12 levels unless the patients supplements with B12. HOWEVER, THAT DOES NOT MEAN YOU WILL GET PERNICIOUS ANAEMIA.
As you know, I take 7.5 mg/day of Deplin, and you can bet your boots that I take 3 mg/day of methyl-B12 and 50 mg/day of P-5-P with my Deplin. The neurochemistry and the published research make it a no-brainer. When taking a large amount of folate, supplementation of methyl-B12 is prudent.
Jan, in addition to Deplin, there are currently two other perscription products and one OTC that are authorized to contain Metafolin (i.e.; L-methylfolate). Here are the three corresponding websites. What I want you to notice is that every one of them has methyl-B12 in them. Ummm. Coincidence ya think?
http://www.cerefolinnac.com/index.php
http://www.metanx.com/ (scroll to bottom for ingredients)
http://www.hsfighters.com/ingredients.htm
As a side note, the previous site has a good explanation for why methyl-B12 is needed instead of cyanocobalamin. Here's the page:
http://www.hsfighters.com/b12_case.htm
Jamal, Racer, and Jan; here is a very interesting and in-depth presentation by Rodrigo O. Kuljis, M.D. on the topic of using L-methylfolate to tx elderly pts with cognitive decline and the need to supplement the L-methylfolate with methyl-B12. The neurofunctional diagrams presented are applicable to young and old alike, and show the need for the co-administration of methyl-B12 with L-methylfolate.
Here is the link. The presentation should start as soon as you click the link, so have your speakers turned on. If it does not cue up on its own, click the yellow box entitled "A New Option for Memory Loss" in the left hand menu column. The presentation lasts about 20 minutes.
http://www.cerefolinnac.com/HealthcareProfessionals,NewOptionForMemoryLoss
-- Ron
BP II w/ultra rapid cycling; and OCPD
300 mg/day Trileptal
200 mg/day Lamictal
250 mg/day Keppra
82.5 mg/day Nardil
25 mg/day Topamax
7.5 mg/day Deplin
poster:Ron Hill
thread:809173
URL: http://www.dr-bob.org/babble/20080124/msgs/809694.html