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Re: SLS Stuff. » deniseuk190466

Posted by SLS on January 9, 2008, at 19:25:40

In reply to Re: SLS Stuff., posted by deniseuk190466 on January 8, 2008, at 17:00:09

Hi Denise.

Thanks for the well-wishes.

All I can say is that it is hard to believe. It doesn't compute with me to be on my way to wellness. It feels almost surreal that my odyssey should come to a happy conclusion.

> It's good to see that you still lurk occasionally, I often think about you as inspite of your illness you have always managed to be able to impart really good, reassuring advice and wisdom to others on this board.

I think I'm "rusty". I'm flattered that you should think such things of me. Thanks.

Is there more information you can add?

Which MAOIs has he tried? Results?

Tricyclics are generally contraindicated for bipolar disorder. They have the highest rate of producing a manic reaction. That explains what your friend has experienced. It sounds like he had a drug-induced mixed-state mania or manic dysphoria. Irritability and/or episodes of rage are the hallmark symptoms of this condition.

I think that Wellbutrin + Lamictal + Deplin might produce some improvement. Should there be no improvement, adding Lexapro would be one alternative if he can tolerate it. Very important is to understand that Lexapro can produce anxiety at the 2-week mark, but this usually dissipates by the end of week 3. If necessary, add Abilify or Geodon.

Of course, MAOIs are good choices for bipolar disorder. Conventional wisdom points to using Parnate as a first choice. All of the aformentioned drugs are available to combine with an MAOI except for Lexapro. In my estimation, there is no safe dose of an SSRI or SNRI to combine with an MAOI.


- Scott


>
> Glad you are still doing well.
>
> I have been writing to somebody who suffers from Bipolar disorder but has been in the grip of mainly depression for the last two years. He has tried tricyclics amongst many other drugs to no avail. The tricyclic made him really irritable and angry so he tells me.
>
> If you have any suggestions for him (based on your own experiences) then please let me know.
>
>
> Denise
>

 

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