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Ketamine rapid BDNF boost

Posted by linkadge on December 18, 2007, at 21:53:49

In reply to Re: Ketamine Trial, posted by iforgotmypassword on December 14, 2007, at 5:25:47

The notion that ketamine can produce rapidly acting antidepressant effects is paralelled by its ability to acutely raise BDNF levels.

http://lib.bioinfo.pl/pmid:17884272

Note, that the comparitor drug imipramine did not acutely rase BDNF levels. Giving raise to the hypothesis that acute BDNF modulation might be behind the antidepresant effects.

Linkadge


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URL: http://www.dr-bob.org/babble/20071213/msgs/801520.html