Posted by amigan on December 6, 2007, at 12:16:11
In reply to Selegiline or Moclobemide? - Help me decide, posted by amigan on December 3, 2007, at 13:30:57
Ok, back on the subject...
I could appreciate some additional feedback on the questions i have posted. Preferably from people who have tried both substances, but all reports are welcome. I can't believe that noone here has tried both of them.
> Hello everyone.
> I didn't got any feedback on this subject in the previous thread, thus i thought to open a separate thread about this. I guess it's because Moclobemide has not been approved in the usa. :-D
>
> Condition: I don't suffer from depression. I have social phobia, agoraphobia and i'm somewhat dysthymic.
> Treatment: I'm currently taking Diazepam + Fluoxetine (Prozac).
>
> The benzo is ok but i am... not sure that Prozac does much for me, so i want to try a MAOI.
> I know that Nardil is the right MAOI for SP etc, but it's not available in here. Not even Parnate.
> I have to chose between Selegiline (Deprenyl) and Moclobemide (Aurorix). Which one do you think that it would be most effective for phobias?
>
> Also which of the two is the more activating medication?
> Diazepam make me drowsy and i could use some up-lifting. I suspect that it's Moclobemide, as it's a MAOI-A and it boosts Epinephrine+ NorEpinephrine+ Dopamine!, (Serotonine is not activating) while Selegiline only boosts dopamine at <=10mg... Right?
> On the other hand, Selegiline is metabolized into L-(meth)Amphetamine, BUT i read that the l- isomer is not considered to be psychoactive at all! It has only peripheral action.
>
> PS: Another question sprung to mind since i've being digging this forum to find some answers to my questions: Why almost everyone here, writes (more or less) that Moclobemide is cr*p, while there so much excitement for Selegiline? "On paper", Moclobemide looks so much better. (see above info) There is got to be a reason. Perhaps Selegiline does some additional stuff that i'm not aware of?
>
> Thank you.
poster:amigan
thread:798497
URL: http://www.dr-bob.org/babble/20071204/msgs/799130.html