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Re: Dopaminergics: Hazardous in long term? » Mishal

Posted by anonymoose on November 22, 2007, at 6:08:16

In reply to Re: Dopaminergics: Hazardous in long term? » linkadge, posted by Mishal on November 22, 2007, at 4:19:25

Mishal,

Do you have any other parkinsonian symptoms? I have a few symptoms myself that could be considered "parkinsonian-like." None of which I can remember having before my dysthymic/anhedonic problems started about 10 years ago.

- jaw tremor (constant, involuntary chattering of the teeth; no bruxism/griding, though)
- hand tremor (appears whenever dysthymic symptoms worsen)
- restless legs (constant)
- memory loss (procedural memory impaired more than declarative; prompting definitely elicits improved recall; I can still kick ass at Jeopardy! but have to re-learn the same programming skills week after week required for my job)
- hypophonia and alogia (in correlation with the severity of the dysthymia)
- masked facial expression (in correlation with severity of the dysthymia)
- micrographia (i can't even read my own handwriting anymore)
- worsening motor coordination
- excessive daytime somnolence (this was the first symptom I ever noticed; eventually falling asleep in *every* class of every day, or every time i tried to read something over a page long)
- oily skin and face


I referenced most of these symptoms off the Wikipedia page for PD. I don't think I actually have PD, but rather feel these symptoms are the result of worsening dopaminergic deficits, the original cause of which I'm unable to identify. Before it all started, I was a happy, well-functioning teen.

I'm now going on day 4 of Mirapex 0.75mg tid and Selegiline 5mg/day. Nothing really profound yet. But I did just add B-complex supplementation which I think might make a big difference for me, too. Currently my complete cocktail is:

1. Mirapex 0.75mg/tid
2. Selegiline 5mg/day

3. ENADA NADH 5mg/day
4. One-a-Day Men's Health Multivitamin
5. B-complex (Walgreen's brand)
6. DL-Phenylalanine (DLPA) 800mg/day
7. Omega-3 fish oils 2000mg/day

I may add some TMG or magnesium, eventually, to see if they help.

Still keeping my fingers crossed for a good sustained therapeutic response from either/both the Mirapex/Selegiline.

-J


> > Do you genuinly have parkinsonian symptoms?
>
> Most probably yes. I do have tremors in my hands that been worsened after being on SSRIs.
>


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URL: http://www.dr-bob.org/babble/20071115/msgs/796516.html