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Re: SSRI Weight Gain and Orlistat (Xenical and Alli) » James_Glasgow_UK

Posted by kaleidoscope on November 19, 2007, at 14:57:44

In reply to Re: SSRI Weight Gain and Orlistat (Xenical and Alli), posted by James_Glasgow_UK on November 19, 2007, at 0:26:33

Hi J

Metformin is a phenomenally widely used antidiabetic drug. It is certainly the most frequently prescribed antidiabetic in the UK. Serious side effects are rare but it does cause quite a lot of gastrointestinal disturbances! Metformin hasn't received anywhere near as much study as a weight loss drug compared with orlistat and is not licensed for this purpose. On the other hand, metformin is cheap and has a good safety record. A small starting dose and gradual dose increases are recommended to minimise GI adverse effects.

Good luck :)


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