Posted by florence on November 8, 2007, at 6:19:23
In reply to Provigil: Agitation, Excitement..B/C ofOverdosing?, posted by Mishal on October 31, 2007, at 9:21:23
I have taken it for 4 yrs- off and on. It most DEFINITELY DOES cause agitation, irritibility- over sensitivity- crying; even irrational thinking. Be careful!
I started with 100 mgs in the am.
Always got a headache when it wore off AND my mood fell and I cried for no reason. SO I always had to take Xanax with it.The more I take at one time- the worse the "fall"
I have taken 100 mgs, 200mgs------now was up to 600 mgs! I am a 50 yr female who weighs 100 lbs!My only medical problem was a 20 yr UNdiagnosed Hashimoto's Autoimmune Thyroid Disease.
It is habit-forming- at higher doses it can induce/inhibit certain CYP3A4 substrates...
Every time I have stopped taking it for a month or more... then restarted, the first day or two was great...Then it lost any benefit.
"The effective elimination half-life of modafinal after multiple doses is about 15 hours. ....Steady states of total modafinal and the l-isomer (metabolite, I think) are reached after 2-4 days of dosing."
florence
poster:florence
thread:792504
URL: http://www.dr-bob.org/babble/20071104/msgs/793887.html