Posted by Meagan on October 12, 2007, at 14:24:00
In reply to Re: Please help w new ? about selegiline prozac combo » Meagan, posted by Larry Hoover on October 11, 2007, at 20:27:04
Thank you Lar, I did indeed mean that selegiline at higher doses would inhibit serotonin breakdown, similar to prozac.
BTW, did you read Dopamine's comments about "sub" serotonin syndrome and possible "silent" heart valve disease with the combo I'm taking? What do you think? I have read the articles on Phen-Fen, but is it too simplistic to equate what happened to patients on Phen-Fen with the combo I am presently taking?
I'm seeing my pdoc in NYC tomorrow and the risk/benefit issue you bring up is precisely what I attend to bring up with him. Thanks
Meagan
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> I'm confused by this comment. Fluoxetine has no MAOI activity that I ever recall hearing about. As you increase the dose of selegeline, there is more inhibition of serotonin breakdown. Maybe that's what you're thinking of, as fluoxetine is a serotonin-reuptake inhibitor.
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> In my opinion, you've pushed the envelope much further than I ever would consider. On a risk-benefit analyis, your lack of response so far does not justify the increased risk you would take by increasing selegeline dose. I'm glad you're under medical supervision, but I also suggest that you learn all you can about the symptoms of serotonin syndrome. Just because you haven't had it yet doesn't mean you won't develop it, even without increasing anything further.
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> Lar
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poster:Meagan
thread:788058
URL: http://www.dr-bob.org/babble/20071009/msgs/788762.html