Posted by psychobot5000 on September 29, 2007, at 13:21:09
In reply to Re: Any can explain me how does SSRE (Tianeptine), posted by Netch on September 28, 2007, at 15:30:57
SSREs are not just another way to line the drugmaker's pockets. Tianeptine works, for some but not others, just as SSRIs work for some but not others. For me it provides better anxiety control and equal antidepressant effect, with no observable side-effects, for which I'm very grateful.
I aree with medweirdo that the situation merely indicates how little is known about depression. There are dozens of antidepressants with very different profiles and mechanisms of action, and they all work somewhat. No one really knows why.
For what it's worth, tianeptine also raises levels of dopamine in certain areas of the brain, by about twenty percent, and reduces the release of acetylcholine. Either could conceivably be related to its antidepressant action.
> According to wikipedia SSRE have less side-effects and provide better anxiolytic effect.
>
> http://en.wikipedia.org/wiki/Tianeptine
>
> The contradictiveness between SSRE and SSRI really illustrates how little science knows about depression.
>
> /Netch
poster:psychobot5000
thread:785664
URL: http://www.dr-bob.org/babble/20070929/msgs/785896.html