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Re: Does seroquel have anti-depressant effects?

Posted by linkadge on September 28, 2007, at 23:08:58

In reply to Re: Does seroquel have anti-depressant effects?, posted by johnj on September 28, 2007, at 16:05:51

Yes, and no. According to wikipedia, Zenica is trying studies for depression?

I think this is a waste of time. Seroquel may have some mood elevating effects, but it is still an antipsychotic.

I think one of its metabolites is a NRI, with less afinity for dopamine receptors.

I don't personally think it is an ideal antidepressant for many people and should probably be reserved for mood problems in bipolar or schizophrenia.

To use it at antidepressant doses, you are risking TD/EPS/diabeties/cataracts/heart rhythem irregularities that one shouldn't need to risk with an AD.

IMHO.

Aprroving this drug for depression would be a step back in safe pharmachology IMO.


Linkadge


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