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Re: How long for Lamictal to clear your system?

Posted by JayBTV2 on September 25, 2007, at 16:02:53

In reply to How long for Lamictal to clear your system?, posted by Jimmyboy on September 25, 2007, at 15:06:27

Maybe you've seen this but from Crazymeds.org - I don't have any personal experience as it's been a pretty good med for me:


Lamictal's Half-Life & Average Time to Clear Out of Your System: Get out a dartboard or some percentile dice, because a random number is going to be just as good as anything. The folks at GSK really tried to pin down a number for Lamictal (lamotrigine), but it so depends on what other medications you're taking, if you take it once a day or twice a day, how much you're taking, how old you are and where a woman is in her monthly cycle. Taking Lamictal (lamotrigine) once a day with no other medications produced a range of half-lives from 14 to 103 hours with an average of 32.8 hours. Taking it twice a day produced a range 12 to 62 hours with an average of 25.4 hours. The aggregate half-life given for Lamictal is 26 hours.

If you're taking a valproate medication (Depakene (valproic acid), Depakote (divalproex sodium) or Depacon (valproate sodium)) the half-life shoots up to 70 hours. If you're taking an enzyme-inducing anticonvulsant like Dilantin (phenytoin), Tegretol (carbamazepine USP), Trileptal (oxcarbazepine), Mysoline (primidone) or good old phenobarbital the half-life is cut to about 13 hours.


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poster:JayBTV2 thread:785126
URL: http://www.dr-bob.org/babble/20070919/msgs/785132.html