Posted by ttee on September 14, 2007, at 19:00:59
In reply to Re: News - Antidepressants Vindicated? » fuzz54, posted by linkadge on September 14, 2007, at 14:24:56
Link - Didn't they do longer term (12 months) studies on Effexor, and Emsam? I thought that they ran the studies out 12 months and randomized the active group with placebos to see if they relapsed.
> >I was told by my therapist (who is now a doctor >doing psych research) that the placebo effect >can be very real in the short-term but loses its >effectiveness over the long-term. Anyone ever >see any studies on this?
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> This is kind of an unsubstantiated argument.
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> The bulk of antidepressant data is on trials that are done for such a short period of time. The drug company only needs to show that a drug is better than placebo for a number of weeks. How then do we really know if antidepressants outperform placebo in the long run? How do we even know that antidepressants "work" in the long run? We don't. There is a severe lack of good long term trial data.
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> The statment "only the true antidepressant effect will stand the test of time", can be used any way you like!
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> For instance, when an antidepressant poops out, some would argue (conviently) that there was no "true" responce to begin with so there really can be no "poop out". Ie, it is possable to have a placebo responce to an active drug.
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> Then its kind of a free for all.
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> Linkadge
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poster:ttee
thread:781684
URL: http://www.dr-bob.org/babble/20070911/msgs/782949.html