Posted by linkadge on August 29, 2007, at 20:44:57
In reply to Re: Still no cure for my depression - tried everyt, posted by jhj on August 29, 2007, at 0:29:57
>I have social anxiety,GAD and depression since >childhood.And i do not recall any traumatic or >stressful event taking place in my life till yet.
k
>As far as animal models are concerned,they can >not be taken seriously.I have seen thousand >things being investigated and drugs found using >mice and rats.But,It does not lead to anything >in the end.
Actually, it leads to a lot in the end. %99 of the psychiatric drugs we take today were likely originally identified for their activities in rodents.
>You mean to say what happens to rats is more >believable then my own case? If i had been >normal in childhood,i would have easily said my >childhood was as good as anyone.
No, what I said is not being taken correctly. I did not say that some depression may not have a biological origin, I am just saying that as of this date, we only really have leads, or hints as to specific biochemical abnormalities.
>No stressfull events but still terrible mental >problems.Can yot tell me what your animal model >suggests in my case "conclusively"? Thanks.
Take obesity for example. I am sure there are some people who are obese who have absolutely no controll over their illness (ie purely genetic). We do know, however, that obesity is on the rise, so, unless this bad gene is multiplying at an exponential rate, one must consider the influence of other factors.
As of this date, no one gene has been identified as being responsable for depression, nor has any one diagnostic marker been definitivly outlined. While I am sure, that some people's depression may be solely due to a bad gene, I would argue that for a large number of with depression, environmental factors play a role in the progression of their disease.
Environmental factors needn't always be "stress". Just as environemntal toxins can cause selective dopaminergic neurotoxicity, perhaps some sort of serotonergic neurotoxin is the cause of an individuals depression. Nutritional imbalences may also be at the heart of certain depressive states.
For some people, considering their disease as a purely genetic one perhaps helps relive some of the guilt associated with the depressive state.
In the end though, there is little proof than any one person's depression is a purely genetic phenomina.
Linkadge
poster:linkadge
thread:775476
URL: http://www.dr-bob.org/babble/20070824/msgs/779615.html