Re: Restless Legs Syndrome-CONGENTIN » jerrypharmstudent

Posted by Phillipa on July 23, 2007, at 23:49:49

In reply to Re: Restless Legs Syndrome-CONGENTIN, posted by jerrypharmstudent on July 23, 2007, at 23:40:35

Jerry well something is better than nothing. Love Phillipa

Benzatropine
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Benzatropine
Systematic (IUPAC) name
3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
Identifiers
CAS number 86-13-5
ATC code N04AC01
PubChem 1201549
DrugBank APRD00748
Chemical data
Formula C21H25NO
Mol. mass 307.429 g/mol
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life 36 hours
Excretion ?
Therapeutic considerations
Pregnancy cat. C(US)

Legal status
Routes oral, IM, IV
Benzatropine mesilate (INN, commonly known as benztropine; marketed as Cogentin) is an anticholinergic drug principally used for the treatment of:
Drug-induced parkinsonism, akathisia and acute dystonia;
Parkinson disease; and
Idiopathic or secondary dystonia.
[edit] Indications
It is used in patients with schizophrenia to reduce the side effects of antipsychotic treatment, such as parkinsonism and akathisia.
Benztropine is also a second-line drug for the treatment of Parkinson's disease. It improves tremor but not rigidity or bradykinesia.
Benztropine is also sometimes used for the treatment of dystonia, a rare disorder that causes abnormal muscle contraction, resulting in twisting postures of limbs, trunk, or face.

[edit] Side effects
These are principally anticholinergic:
Dry mouth
Blurred vision
Cognitive changes
Constipation
Urinary retention
Tachycardia
Anorexia
Psychosis (usually in overdose)
Some studies suggest that use of anticholinergics increases the risk of tardive dyskinesia, a long-term side effect of antipsychotics.[1][2] Other studies have found no association between anticholinergic exposure and risk of developing tardive dyskinesia.[3]
[hide]v • d • eAnti-parkinson drugs: anticholinergic agents (N04A)
Tertiary amines Trihexyphenidyl - Biperiden - Metixene - Procyclidine - Profenamine - Dexetimide - Phenglutarimide - Mazaticol - Bornaprine - Tropatepine
Ethers chemically close to antihistamines Etanautine - Orphenadrine
Ethers of tropine or tropine derivatives

Thread

Restless Legs Syndrome? jerrypharmstudent 7/17/07
...
Re: Restless Legs Syndrome? » jerrypharmstudent cactus 7/18/07
Re: Restless Legs Syndrome? » jerrypharmstudent Zyprexa 7/19/07
Re: Restless Legs Syndrome? » jerrypharmstudent OzLand 7/19/07
Re: Restless Legs Syndrome? » jerrypharmstudent cactus 7/20/07
How I beat RLS and discovered ADD. smpayne69 7/20/07
Re: How I beat RLS and discovered ADD. » smpayne69 cactus 7/20/07
Re: How I beat RLS and discovered ADD. smpayne69 7/20/07
Re: How I beat RLS and discovered ADD. » smpayne69 jerrypharmstudent 7/22/07
Re: How I beat RLS and discovered ADD. » jerrypharmstudent smpayne69 7/22/07
Re: How I beat RLS and discovered ADD. » smpayne69 jerrypharmstudent 7/22/07
Re: How I beat RLS and discovered ADD. smpayne69 7/22/07
Re: Restless Legs Syndrome-CONGENTIN jerrypharmstudent 7/23/07
Re: Restless Legs Syndrome-CONGENTIN » jerrypharmstudent Phillipa 7/23/07
Re: COGENTIN-thanks you (nm) (nm) » Phillipa jerrypharmstudent 7/24/07
SMpayne69.... spriggy 7/24/07
Re: SMpayne69.... smpayne69 7/24/07

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