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Re: How abou this:Desipr.+paroxet+selegiline?

Posted by Darkness At Noon on July 23, 2007, at 9:28:02

In reply to How abou this:Desipr.+paroxet+selegiline?, posted by trotten on July 23, 2007, at 4:07:43

> I wastaking cynbalta foe a long time,but I felt it poped-up. So I decided to use desipramine 200mg/day. paroxetine 40mg/day andin a few days putted selegiline(oral form)20mg. This combo is an triciclic plus SSRI and a MAOI. Soon I'll add SAMe.
> So what do you think about this?

Are you doing this in consultation with your pdoc? Almost everyone (FDA, pdocs, patients) seems to think combining MAOIs with SSRIs like Paxil is an invitation to serotonin syndrome. To a lesser extent, they're afraid of hypertensive crisis when combining MAOIs with tricyclics, although perhaps less so with with TCAs like desiprimine, which has less serotonergic effect.

I'd advise checking this out with a competent pdoc ASAP.


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poster:Darkness At Noon thread:771297
URL: http://www.dr-bob.org/babble/20070719/msgs/771317.html