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Re: Mood stabilizers vs. Benzos

Posted by linkadge on July 21, 2007, at 19:41:33

In reply to Re: Mood stabilizers vs. Benzos, posted by SheilaC on July 20, 2007, at 6:48:54

Benzo's are sometimes used as mood stabilizers. The only real advantage of lithium/depakote vs. a benzo, is that apparently, lithium/depakote have more effect on some of the genes that may be involved in bipolar (ie PKC, BCL-2, GSK-3b) etc.

These two mood stabilizers are also neurotrophic, while the benzo's are not.

If you do not respond well to lithium or depakote, then I don't see why a benzo is a bad idea, as the other mood stabilizers, (ie lamotrigine, gabapentin, topomax etc), do not share lithium/depakotes ability alter PKC etc, and so are no more "bipolar specific" then the benzo's


Linakdge


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URL: http://www.dr-bob.org/babble/20070719/msgs/771037.html