Posted by dewdropinn on July 20, 2007, at 9:19:13
In reply to Re: May i be blunt, posted by steel on July 18, 2007, at 16:33:23
Deprenyl at any dose would probably be not such a good idea -- even at a tiny dose, it would increase the MAO-B inhibition that's already occuring with Parnate. While you wouldn't need fear serotonin syndrome, you would be at serious risk of triggering a hypertensive crisis. The internet drug vendors are doing a major disservice by presenting Deprenyl as a drug with boundless potential while glossing over the dangers -- selegiline is a great drug -- I can't say enough positive things about the patch when taken at the higher dosage levels -- and it's a very safe drug, so long as you are aware of the drug-drug interactions. As a final note -- I almost bought the farm by combining low dose selegiline with Zoloft years ago, which is why I'm urging caution on this one. As you note, the classic stimulants are definitely a viable and proven augmentation option with MAOIs -- I've taken dexedrine with selegiline in the past, and it posed no problems whatsoever.
I wonder -- why are you dead set against lamictal? So long as you follow the titration schedule, it's one of the safest and least toxic drugs available -- and unlike every other mood stabilizer on the market, it does not significantly impact liver or kidney function, it has minimal to no endocrine side effects (unlike all anti-psychotics and just about every other anti-convulsant), and virtually no cognitive side effects for the vast majority of people who take it. Epileptics take the drug at truly heroic doses, and it has proven safe and effective for long-term use even when taken at ludicrously high doses. Keppra is extremely non-toxic, but it has a major impact on mood -- like you, I literally became a rageaholic overnight, so for the sake of my social life, I bagged it within days of starting. So from a safety, tolerability, and efficacy standpoint, you probably won't find a better first-line option. I have taken 400mg daily for several years, and it's been a godsend -- it enhances mood, energy, clarity of thought, reduces anxiety. It's the foundation of my regiment. I currently take 400mg of Lamictal along with the 9mg EMSAM patch.
Best of luck,
Drew
> > > > Why can't parnate/neurontin be repeated?
> > > >
> > > > Sorry to add another ? in your ?s!
> > > >
> > > > 5f
> > > No its me im simply bad with words.What i mean there is its not as simple as the one combo dose taken,works to a degree,then i can simply say....
> > > i waited,now i repeat the same combo,i get the benifit from the first time of the combo,and thats it,if i tried to simply lower the dose and repeat the initial med combo it wont work well,make sense?
> > >
> > > Kinds like a big coffee works great in your am,does what you like,however 4 hrs after no more benifit,then repeating that coffee,at the same size or lower wont be the same.Lol hope this analogy helps a little.
> > >
> > > Seeing my doc today,im hoping to add keppra in.
> >
> > I took Adderall XR with Parnate. It enough to get me through the work day. I also got a boost from my afternoon dose of Parnate, which most people don't seem to get, unfortunately. By the way, how much Parnate are you taking?
> >
> >
>
> A older doc gave me ritalin with parnate,shes long gone,has moved.Ive racked my brain just going through local docs in the are who would eve simply keep me on my already established parnate dose,or parnate period.
>
> I have one now,however i think hed cringe if i mentioned adding adderall lol.My dose is 40 mg 2 a day but at times ill attempt to break it up to possably 20 mg then then etc trying to get my brain to snap out of the possably appearent adaptaion it has accustomed itself to with me.
>
> Keppra set me angry as a pit bull on day two,least im almost sure of it,scared to start it again.I just think i need additonal anti depressant effect,and is why all these bipolar meds,lamictal etc one after the other being added never help my situation.
>
> I am thinking of adding liquid deprenyl in small doses soon to parnate?
poster:dewdropinn
thread:769601
URL: http://www.dr-bob.org/babble/20070719/msgs/770702.html