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Re: Decision about switching from Parnate to Nardil?

Posted by Jedi on July 7, 2007, at 4:00:24

In reply to Decision about switching from Parnate to Nardil?, posted by Shaner on July 5, 2007, at 12:57:06

Hi,
I've been on MAOIs for most of the past ten years(mostly Nardil). I would give the Parnate at least six weeks. When I was taking 80mg of Parnate it took eight weeks for the afternoon tiredness to wear off. Many times I ended up taking two hour naps, which really didn't help the evening insomnia.

Even though they are both MAOIs, Parnate and Nardil are very different medications. Some people will respond to one while the other does nothing for them. Then there is augmentation. Many PDOCS really hate to mix anything with a MAOI, but in the right hands a lot of combinations are possible. I've taken nortriptyline, bupropion, and other non-serotonergic medications with Nardil. Many people here have used stimulants with MAOIs. Lithium is probably the most researched of the augmentation medications, and helps many unipolar as well as bipolar patients. There are always options.
Be well,
Jedi


> In the last month I've been taking Parnate and had some success at first with 10-20mg, followed by going downhill as I increased the dose to 40mg. My fatigue and anxiety actually increased. Now back down to 20mg for the last few days I feel somewhat better. This has often been the pattern for me with other meds before. Should I be satisfied with a partial success or try Nardil? It sounds like Nardil is usually better for anxiety and social anxiety, which sounds appealing to me. I thought Parnate would be better since it's often more stimulating and fatigue and lack of motivation are a major part of my problem. But I haven't had any miracles in that area yet. For those of you who have read these sites often, would you say you've noticed many who have a much better success with Nardil after a partial success with Parnate?


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