Posted by steel on June 21, 2007, at 12:03:45
In reply to Re: weird parnate side effects after one week » malcolm664, posted by Quintal on June 20, 2007, at 18:46:09
> >And why would you ever think that an MAOI is energizing? After all, it's supposed to diminish anxiety and drugs that do that are by nature always sedating
>
> I think we've discussed this before - MAOIs are often stimulating (probably because they shore up noradrenaline and dopamine). Nardil is sedating mainly due to the action of the metabolite PEH (phenylethylidenehydrazine), which elevates levels of GABA in the caudate-putamen and nucleus accumbens. Nardil is unique among MAOIs in having this effect, and not all MAOIs are anxiolytic by any means.
>
> Q
I agree,i also feel that although not to the EXTENT nardil is mentioned,that however parnate if archived to recent vs long ago posts there is a differeance to its energizing effects.Was the drug toned down some,could we ever actualy know for sure?
Also even with caffiene or actualy the addition of caffiene i have actualy feel asleep on parnate more readly,however it is a nice anti depressant sleep as i wake up feeling ok,so its not a big problem.
Just goes to show how the brain is obviously not so 1,2,3 like working on a car as we are wishing it were.
p.s caffiene tabs are pure caffiene,coffe grind has sedating properties which is why more people get anxious without morning coffee then say morning mountain due.Coffee is both a stimulant and the grind produces a calming effect.People might want to visit there local 7 11 for awake tabs which in various brands are usualy simply nothing more than pure caffiene 250 mg no inactive ingredients.
poster:steel
thread:764524
URL: http://www.dr-bob.org/babble/20070613/msgs/764725.html