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Re: Standing in the shadows

Posted by linkadge on June 16, 2007, at 17:12:24

In reply to Re: Standing in the shadows » linkadge, posted by Squiggles on June 16, 2007, at 16:08:23

>It's not nonsensical-- it's all over the medical >sites and PubMed on the net. Do some research.
>What kind of proof do you want- a lemming parade?

Yes it is (IMHO). There has not been any conclusive proof that antidperessants reduce the risk of suicide. A few small studies on pub-med do not show whats happening overall. The rate of suicide has not taken a significant drop since the introduction of antidepressants. In some regions the rate of suicide has decreased since the introduction, while it has increased in other regions. Overall, there is no significiant reduction in suicide since the introduction of antidepressants.

>In this case that I know - it was the reduction >in imipramine dose that led to suicidal ideation
>and attempt.

The drug itself may not have been preventing suicide. Perhaps it did nothing for suicidal ideation. Perhaps the hell of drug withdrawl was combining with the current state to push a person over the edge?

>Furthermore, the psychiatrists raised the dose >precisely for that reason-- to prevent suicide-- >you think they are nonsensical? All of them?

No, just misguided. A doctor prescribes a drug because it is supposed to decrease depression, and because a decrease in depression is supposed to reduce suicide. It doesn't work that nicely though. A drug company does not need to proove a drug reduces suicide for it to be approved. Therefore the antisuicide effect is just assumed.


>Good for you-- i hope he's not your son, as we
>seem to be speaking hypothetically.

My parents had absolutely no clue how I actually felt on antidepressants. My parents and the doctors just believed what they wanted to. My depression did not reduce on AD's, they just shut me up and made me more managable. I just told them I felt better so that they'd stop bothering me. Thats what they wanted to hear.

If my son wanted to stop imipramine I'd tell him to go for it. Imipramine is both genotoxic and cardiotoxic. Only he'd know how the drug made him ultimately feel. Imipramine is dirty. A lot of people have a hard time tollerating it.

Linkadge


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URL: http://www.dr-bob.org/babble/20070613/msgs/763611.html