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Re: Librium (chlordiazepoxide) - outdated nowadays

Posted by James_glasgow on June 12, 2007, at 19:23:15

In reply to Re: Librium (chlordiazepoxide) - outdated nowadays » James_glasgow, posted by kaleidoscope on June 12, 2007, at 15:08:25

Hi Ed

Have you ever noticed how the BNF states that chlordiazepoxide base is equivalent to chlordiazepoxide hydrochloride. This would only be the case if the dose of the hydrochloride salt was equivalent to the same number of milligrams of the base. As it is on everything else, i.e. i think it is something like 22.8mg (I cant be bothered working it out at the moment) is the equivalent of 20mg of paroxetine. Howver, with chlordiazepoxide I have never seen the same thing, probably because I have not myself seen the 1000 cap or tab containers. Do you know if they are really equivalent i.e there is more than 5mg of chlordiazepoxide hydrochloride in a capsules or a tablet. I once tried to argue it with a pharmacist in Boots, got as far as mentioning stiochiometry and she did not have a clue what I was talking about.

Regards

James


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