Posted by Tomatheus2 on June 11, 2007, at 18:14:41
In reply to Re: Combining Provigil and Parnate » Tomatheus2, posted by gardenergirl on June 11, 2007, at 7:56:15
> Actually, the two meds are not contraindicated, but rather caution is advised if using the two together.
gg,
The 2004 abstract that I linked to in my previous post stated: "The concurrent use of [tranylcypromine and modafinil] is normally contraindicated based on theoretical concerns."
However, the prescribing information document for Parnate does not state that the medication is contraindicated with modafinil, which (based on my understanding of things) should mean that the two meds are not officially contraindicated. I think that it would have been best if I had referenced Parnate's prescribing information document before stating that the medication is contraindicated with modafinil (based on a sentence in a case report's abstract). I apologize for my statement. I think that you're correct in stating that tranylcypromine and modafinil are not contraindicated, and I should not have jumped to conclusions so quickly.
Tomatheus
==
Sources:
* 2004 case report on the concomitant use of modafinil and tranylcypromine in a patient with narcolepsy:
http://linkinghub.elsevier.com/retrieve/pii/S1389945704001145* Parnate tablets prescribing information:
http://us.gsk.com/products/assets/us_parnate.pdf
poster:Tomatheus2
thread:761881
URL: http://www.dr-bob.org/babble/20070604/msgs/762434.html