Posted by hgi698 on June 10, 2007, at 20:40:45
In reply to Re: 1 mg Mirapex Cause Of Compulsiveness? » Quintal, posted by flame on June 7, 2007, at 8:26:07
Pramipexole has been shown to produce significant impairment of short term verbal memory, attentional-executive functions and verbal fluency. That effect coupled with the drugs ability to stimulate dopamine receptors in the nucleus accumbens (pleasure center) could lead to compulsive, mindless reward seeking.
Here's the link for the memory impairment study.
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12658365
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