Posted by Quintal on June 8, 2007, at 18:16:53
In reply to Re: Depression is unfortunate brain chemistry » linkadge, posted by Squiggles on June 8, 2007, at 11:36:42
Which brings me back to opiates. Why is the opiate deficiency theory of depression not widely upheld given their rapid and almost universal antidepressant effect? Codeine fulfils the criteria for ideal an antidepressant that you outlined there. It makes just as much sense as claiming dysregulation/deficiency in other neurotransmitter systems is the underlying cause of depression. Even the psychosomatic aches and pains that are common in depression could be held up as evidence of a hypoactive opiate system. But the mood lift after taking opiates doesn't prove that there was ever anything wrong with the opiate system to begin with, because the same person would probably also feel better after taking Esterene for example (a slow-release version of crack cocaine).
http://findarticles.com/p/articles/mi_m1200/is_n25_v136/ai_8207099/pg_3Q
poster:Quintal
thread:761153
URL: http://www.dr-bob.org/babble/20070604/msgs/761889.html