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Re: Mirtazapine

Posted by linkadge on June 4, 2007, at 19:54:13

In reply to Mirtazapine, posted by Squiggles on June 4, 2007, at 19:33:17

>I was looking at one of Dr. Nemeroff's books and >his colleague's (a guide), and this drug >Mirtazpine (a TCA) looks really good.

Remeron isn't a TCA. Not sure of the structure, but it is not reltated to traditional TCA's.

>It has very low anticholinergic effects, thus >good for the heart,

I don't know if one can make this conclusion. The cardiac effects of TCA's are not due to their anticholinergic activity. Remeron can sometimes increase blood pressure and heart rate like other alpha-2 antagonists (yohimbine etc)

>very little hypotension, and easy to tolerate >all-around, with one adverse reaction which >stops when the drug is stopped.

Well, that does sound like a nice (drug book) summary. Remeron has different side effects, but not necessarily less burdonsome. It can be very sedating. It can cause irritability (REM rage) it can also increase the appetite significantly.

>It looks like a drug that might be good for >seniors too.

Well, I don't know.


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