Posted by jflange on May 26, 2007, at 21:56:16
In reply to Re: phillipa » brooke484, posted by Phillipa on May 26, 2007, at 21:29:48
Hi!
I think the reason SSRIs only seem to work on the first dose is that eventually your brain starts to down regulate the neurotransmitters in response to the medication. According to my neurobiology phd friend, it's a more complicated process than that, but the short story is that the therapeutic benefit over time comes from how your body responds to the drug over the long term. That first dose is just the joy that comes from an initial serotonin dose before the body responds.
Brooke- I have read through your posts and agree with the person who suggested Lex and Klonopin. from what I hear from you, I think that DP is really how your body responds to anxiety/ panic attacks. And anxiety is rarely conquered with just one medication. Try a combination, like an SSRI you can tolerate and a benzo or buspirone. That's how I licked depersonalization after suffering from PD/PTSD for a little over 12 years!
Best of luck to you,
jflange
poster:jflange
thread:751993
URL: http://www.dr-bob.org/babble/20070524/msgs/759719.html