Posted by Jedi on May 4, 2007, at 2:30:05
In reply to Re: If MAOIs fail, what then?, posted by FredPotter on May 3, 2007, at 23:28:13
> If Nardil (or Parnate) poop-out isn't it wise to increase the dose? However, I read that after 4 weeks of effective response one can drop the dose right down, as all the MAO has been destroyed and it takes a long time to be restored so a small dose is all that is needed to mop up the new MAO as it is created.
>
> I'm disappointed to hear about MAOI poop-out as I didn't think it did. Also that once once on the right dose it always works
> FredHi Fred,
My strategies listed above are for if the meds quit working all together. Currently, I'm on 80mg of Parnate and doctor willing, I will take it up to 100mg or more if needed. I am already augmenting with clonazepam, but lithium and stimulants are other options I will pursue if necessary. If Parnate does not work for me, this is my 2nd trial-I'm going to push it a lot harder, then I would go back on Nardil. In ten years this medication has never failed me. I don't like some of the side effects, that is why I try other meds. Not saying it is the right thing to do, but I have a stash of Nardil to get me started again. I had a PDOC once who would have let me die before putting me back on Nardil. It took me several months of letter writing to find someone to prescribe it.I've read about the theory of being able to reduce your MAOI dosage after several weeks or months at an effective dosage. All I can say, it does not work for me(n=1). While on Nardil, I have to keep the dosage between 75 and 90mg or it's the "Black Hole". It sure would be nice to reduce it because of the side effects. This strategy may work for some people. I believe there are other things going on with MAOIs besides just Monoamine Oxidase Inhibition.
Good Luck,
Jedi
poster:Jedi
thread:755424
URL: http://www.dr-bob.org/babble/20070502/msgs/755712.html