Posted by linkadge on April 30, 2007, at 18:26:31
In reply to Re: Using Bipolar as a 'fill in the blanks', posted by Johann on April 30, 2007, at 1:31:27
>I appreciate your comments and find myself >agreeing with you. It's a lot easier to hear >what you're saying when you're not so hot under >the collar.
I'm sorry that you got that impression. I am not angry as much as I am frustrated (about my own situation)
>In my case, AD "poop out" was *one* of the >indicators that I might be dealing with some >form of BPD. Then, after having a manic >depression, near suicidal, in response to >disiprimine, it became pretty clear. I have >almost no mania, though; however, a lot of >anxiety.
While this is for a separate topic, I do not believe that antidepressant induced mania is indicative of bipolar.
Here are some of the logical fallacies I see constructed by psychiatrists. While the following may be true some of the time, they are not rules.
1) Antidepressant poop out indicates bipolar
2) Antidepressant induced mania indicates bipolar
3) Response to mood stabilizers indicates bipolar.I believe these are logical fallacies for the following reasons (respectivly)
1) Drugs poop out all the time regardless of diagnosis.
2) There are millions of dollers of reaserch currently being undertaken to research animal models of antidepressant induced mania. Some researchers believe that antidepressants can induce mania in individuals who don't have bipolar disorder. Just as they can induce permanant seizure disorders in some individuals without epilepsy. Antidepressants can activate many genes that are activated in mania, namely PKC, GRK3, CLOCK2, and others. The noradrenergic antidepressants in particular, can significantly reduce rem sleep, which can reduce seizure threshold.
3) There are GABAergic and glutamatergic theories of major depression. Certain depressive disorder may respond to mood stabilizers due to their ability to increase GABAergic neurotransmission and or reduce glutamatergic neurotransmission.
My mother never ever had a manic episode before she was exposed to tricyclic antidepressants. She was just an anxious depressive. She was called bipolar, after high doses of doxapin sent her into a extreme mixed state. Because of this she is now called bipolar (which I do not agree with) and has been placed on lithium.
While lithium has been of some use, she has clearly deteriorated over the last 30 years. Her kidneys are shot, and her memory is gone.
While I hope this doesn't happen to you, I'd just hate to think you were another casualty lead down the garden path.
Again, I don't mean to come across like a a-hole. It is just hard to accept the kind of logic that has changed my mother from a loving caring person to a brain dammaged near vegatable. (I don't say that in a disrespective way at all).
Linkadge
poster:linkadge
thread:753904
URL: http://www.dr-bob.org/babble/20070426/msgs/754709.html