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Re: Not negligable, but not primary effect (?)

Posted by psychobot5000 on April 11, 2007, at 19:02:05

In reply to Re: Not negligable, but not primary effect (?), posted by linkadge on April 10, 2007, at 18:49:43

> From the studies I came across, on average users of ~300mg per day achieved approximatetly 35% inhibition of dopamine reuptake. So yes you are going to get appreciable effect on dopamine uptake, but it is questionable as to wheather this totally accounts for clinical effect.
>
> Linkadge

If I remember right, however, bupropion also decreases dopamine release, leaving a net-effect of a more slight increase in extrasynaptic dopamine.


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