Posted by Quintal on February 20, 2007, at 17:34:12
In reply to Nardil or Parnate?, posted by blueberry1 on February 20, 2007, at 16:26:07
I wouldn't worry about your bad reaction to moclobemide, I've never seen a case where anybody has done well on it, and I felt no effect from it myself at all. I think you're right to go straight for the big guns Parnate and Nardil without trying EMSAM and Marplan. Nardil is the only MAOI I haven't taken and the anorgasmia puts me right off it, as opposed to Parnate + benzo for my anxiety. If depression is your main problem I'd go straight for Parnate and take the dose as high as you can tolerate. Also consider augmenting it with Lamictal and a benzo. I had my best response ever from that combo and Parnate was the major player there I'm sure.
>I wonder if either one could spark a dysphoric mania or turn me into a mean bitch like ECT did. I do not want to take a mood stabilizer. I just need a mood elevator.
That could happen at low doses in the first week. I became much more depressed and even suicidal during the first three days, but that was quickly replaced with euphoria and wellbeing after I raised the dose to 80-120mg. I'd encourage you to push through that until you're taking at least 80-120mg a day for a week.
>Does parnate have sexual dysfunction too? Anorgasmia, impotence, lack of desire, any of those?
I've seen one other poster complain of that but I didn't experience any sexual problems myself and I'm very sensitive to that. In fact, Parnate increased my sex drive and ability. I think it's possible to reverse Parnate sexual dysfunction with cyproheptadine (which will also aid sleep), but I don't think it will be a problem.
>Parnate is stimulating, right? I like that. I guess if it was too stimulating I could mellow it out with a benzo. Worried about a stimulating drug when I have anxiety to begin with.
Parnate felt a lot like coke to me at the doses I described. Maybe that would be especially good with you being an ex-coke user? Perhaps that's exactly what you need to reverse your depression? I took Parnate with 4mg Klonopin and I'm reluctant to take it without a benzo. From my own experiences and from what I've read here Parnate works best with a 'downer' to smooth the jitters and help sleep.
>I can't even remember anyone saying they didn't, except for those who did ok with it then stopped it then went back to it and it didn't work again.
I improved a great deal with Parnate. I agree with Chairman_MAO that Parnate is one of the few true mood elevators among antidepressants as opposed to mood flatteners and anaesthetics like SSRIs.
I'm still thinking of going back to it again and have loads of bottles in my cupboard ready for use when I do. I thoroughly recommend you try it.
Good luck.
Q
poster:Quintal
thread:734552
URL: http://www.dr-bob.org/babble/20070219/msgs/734562.html