Posted by saturn on February 13, 2007, at 21:29:50
In reply to Re: Remeron's hypnotic qualities/mechanism(s), posted by cb_psy on February 11, 2007, at 5:53:26
> according to preskorn, mirtazapine first blocks histamine. So 7,5 mg should just produce grogginess.
> http://preskorn.com/images/columns/0007_fig1.gif
>
> For me higher dosage is more sedating. Ive heard people state otherwise but that is probably due to histamine tolerance you get as time goes by and you raise the dose.That's a really cool graph and site---thanks for the link.
I'm intersted in learning what dose would hit Histamine and 5-HT, but before significant NE effects. I'm guessing around 15(?).
poster:saturn
thread:731008
URL: http://www.dr-bob.org/babble/20070213/msgs/732581.html