Posted by linkadge on February 10, 2007, at 9:08:31
In reply to Amantadine reg. activity in cingulate gyrus 4 OCD, posted by temoigneur on February 10, 2007, at 2:17:10
I would tend to think that most effective treamtments for OCD achieve their theraputic effect by altering regional brain metabolism. I think that theraputic response to SSRI's is also associated with dampening of similar circuits.
The idea that OCD was a disorder of low serotonin is kind of old. The net goal in altering monoamines is probably the same as the intercellular actions of amantadine.
OCD with comorbind ADHD can be difficult to treat as stimulant drugs often have the side effect of increasing directed attention and sometimes "obsessive circutry"
I would start with treating the most distressing of the two diseases fully, and then look to treat the second, hopefully without bringing back the first.
Linkadge
poster:linkadge
thread:731545
URL: http://www.dr-bob.org/babble/20070207/msgs/731563.html