Posted by kaleidoscope on February 9, 2007, at 13:55:32
In reply to Re: Neurontin helpsChills + Sweats when coming off » Alone, posted by yxibow on February 9, 2007, at 3:37:32
Hi J
>"unclean" agents like Prozac
Why do you say that? Fluoxetine isn't a 'dirty drug'. It isn't such a 'selective' SSRI as some of the others (eg. citalopram) but all this means is that it is an extremely weak NE reuptake inhibitor. If this is what you mean by 'unclean', duloxetine (Cymbalta) is much less 'clean' than fluoxetine.
>I wouldn't recommend it as a first line SSRI to someone because once you commit to a dose, its gonna be there for a month, whether you tolerate it or not
Not really. As with all SSRIs, side effects appear rapidly. If someone has only been taking it for a few days, its active metabolite norfluoxetine (the one with a long half life) won't have built up in the body. Fluoxetine itself does not have such a long half life.
Personally, I think that (generic) floxetine is a suitable first-line SSRI for many patients suffering from depression. For elderly people, and for people on multiple medications, generic citalopram is a better first-line SSRI because of the reduced risk of drug interactions. IMO, Lexapro should never be a first-line SSRI because it is so overpriced - its alleged advantages over citalopram are somewhat dubious.
K
poster:kaleidoscope
thread:731257
URL: http://www.dr-bob.org/babble/20070207/msgs/731414.html