Posted by yxibow on February 2, 2007, at 21:23:50
In reply to Re: Stimulants-Please be careful! » yxibow, posted by Reggie BoStar on February 2, 2007, at 8:53:39
> Actually, yxibow, Benzos are only used during Alcohol detox treatments. Once the detox treatments are complete, Benzos are contraindicated. This is why I, along with the vast majority of substance abusers, are not prescribed Benzos after detox treatment is done. Since I never specified why Benzos were contraindicated for me, you were premature in your assumption that I meant detox as well as post-detox recovery.
I know that they are used in detox, that's all I meant. If it came out in any other way, I apologize. Yes, they're most likely contraindicated for most substance abusers unless the use of them far outweighs the potential of misuse.
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> Also, I never said anything about using Buspar as an antipsychotic.
How did I say this ? I was making an observation that BuSpar was an attempt at creating an antipsychotic that was instead placed on the market for GAD.
I referred to it as a treatment for GAD, which you verified by describing it as an anxiolytic. In this context, its lack of success as an antipsychotic is irrelevant. I'm not sure why you mentioned this at all.
I mentioned purely for its medical interest. There wasn't anything there that said you were taking it for psychosis at all.
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> As far as the 1/3 response, that depends on whose study you choose to believe. Among those which include its use as treatment for dual diagnosis (anxiety and alcoholism) conditions as well as GAD, these studies show a higher response:
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> Tollefson GD, Montague-Clouse J, Tollefson SL. Treatment of comorbid generalized anxiety in a recently detoxified alcoholic population with a selective serotonergic drug (buspirone). J Clin Psychopharmacol. 1992;12:19-26.
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> Kranzler HR, Burleson JA, Del Boca FK, et al. Buspirone treatment of anxious alcoholics. A placebo-controlled trial. Arch Gen Psychiatry. 1994;51:720-731.
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> J Clin Psychiatry. 1990 Sep;51 Suppl:40-5. A double-blind, controlled trial in primary care patients with generalized anxiety: a comparison between buspirone and oxazepam. Strand M, Hetta J, Rosen A, Sorensen S, Malmstrom R, Fabian C, Marits K, Vetterskog K, Liljestrand AG, Hegen C. Primary Care Center, Enkoping, Sweden.
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> I would be very much interested in knowing which studies you are citing when you report a 1/3 response rate to Buspar.These are 15 year old studies -- but I'm just coming from common knowledge gathered from experience with a number of doctors that BuSpar works for about a 30% responding rate, which, considering that the responding rate of placebos are 30%, is not a bad amount.
It has a higher effectiveness than 1/3, I will agree for patients with mild GAD. It does not have very successful use in patients with major anxiety disorders such as panic disorder.
Other statements do uphold your success that if one waits long enough, and BuSpar is not a drug initially effective, there may actually be greater effective rates than previously thought. It is not a substitute for a benzodiazepine and will not produce quick results that panic disorders and other high intensity anxiety disorders benefit from agents such as Klonopin, Ativan, Xanax, and Valium.
It does have the advantage (and I understand for you) that it is not addictive as far as we know and is fairly well tolerated except for dizziness which does occur in a certain percentage of people (as did for me, I can't quite describe the dizziness but it was something just not quite right.)
So no worries, I understand that we all can get intense on here at times and I am not offended and it was a compliment that you responded to the medication and I hope you continue to do so.-- tidings
Jay
poster:yxibow
thread:728752
URL: http://www.dr-bob.org/babble/20070201/msgs/729206.html