Posted by tensor on February 1, 2007, at 10:08:50
In reply to Edronax (reboxetine) considering re-trial........., posted by Quintal on January 31, 2007, at 20:55:07
Yes, after a five weeks trial of Zyban, Remeron and Zoloft my mind was set to retry Edronax with the knowledge that tamsulosin might be an antidote for the horrible s/e I experienced last time (2003), I also found an old box of Edronax with almost 60 pills left. About two weeks ago, I did a sneak trial with Edronax just to remember how it affected me, after two doses, the penis shrinkage returned along with pain in the prostate and the testicles. Also the premature painful(!) ejaculation was there and urinating problems with feeling of residual urine after emptying. Very annoying indeed.
I saw my pdoc a few days ago, and when I had told him the Zyban trial was a failure he asked me if I had any ideas of what to do next. I said I once tried Edronax and responded well to it but had to terminate it because of the above mentioned s/e, he checked the med in a reference book and noticed the s/e was mentioned there. I said I've read studies where subjects on Edronax had been treated successfully, 100% relief, with the alpha1 blocker tamsulosin (naftopidil could work too) and wished to try it. He had no objections to the proposal so I got a prescription of tamsulosin and Edronax.
I started full dose of Edronax at tuesday and felt the symptoms return, Wednesday morning I took one capsule of 0,4mg of tamsulosin and the s/e went away after a few hours. Today I have no s/e from Edronax at all, tamsulosin gives me the usual alpha1-block orthostatic hypotension but that's a trade off I can live with. It's several days left before both meds reach steady state plasma level and several weeks before I can give a fair judgement, but it looks/feels promising. I keep my fingers crossed.
/Mattias
poster:tensor
thread:728579
URL: http://www.dr-bob.org/babble/20070201/msgs/728726.html