Posted by blueberry1 on January 23, 2007, at 21:26:46
In reply to Re: Increasing the Effect of Medications » blueberry1, posted by yxibow on January 23, 2007, at 19:53:06
I totally agree. I just thought it was interesting they actually tried that, instead of doing something simple like maybe take the daily dosage and divide into 5 doses instead of 4, or go with the XR version. Adding another med, especially one so sedating like serzone, seems like overkill to me. No way to monitor what is doing what. Too many variables and too much risk.
> > I read an abstract at pubmed.com where they used low doses of the antidepressant serzone to smooth out the peaks and troughs of xanax. Serzone inhibits the enzyme that breaks down xanax.
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> As long as one is careful about Serzone itself, because you're putting three medications through the liver now. Nefazodone has had some liver issues so testing say baseline and 4-6 weeks later would be prudent.
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> But I don't see the point of using other medications to artificially alter P450 enzymes than convincing your doctor you need a little boost of Xanax, and as long as you're taking Xanax you might as well be taking Xanax XR so you don't have peaks and valleys with interdosal withdrawal and you're less likely to develop Xanax tolerance because its a 24+ hour half life.
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> Medicine usually dictates the MED (minimum effective dose) and minimum use of medications and invasive procedures to maintain suppression or elimination of symptoms.
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> -- Jay
poster:blueberry1
thread:725295
URL: http://www.dr-bob.org/babble/20070119/msgs/725767.html