Posted by halcyondaze on January 20, 2007, at 12:38:37
In reply to Re: Specific drugs - any experiences? » halcyondaze, posted by Quintal on January 20, 2007, at 12:18:06
> >3) Estazolam (ProSom)
>
> Yes, I tried it and liked it very much. I read it allegedly has less abuse potential than most other benzodiazepines.
>
> >5) Zopiclone (Imovane - is this available in the US? It's the precursor to the isomer of Lunesta)
>
> Zopiclone is very widely prescribed in the UK and I've taken it many times. It is effective but I can't compare it to Lunesta because it isn't available here.
>
> QWhy isn't Zopiclone available in the US? I'm surprised they approved Lunesta so quickly while its precursor is not available.
That's what I've been looking at (abuse liability) since I have a history of substance dependence (including Xanax) but was able to take meds with a lower potential for abuse like Ambien and Temazepam without abusing them.
There's this terrific paper I've been using: << neuroscience.jhu.edu/griffiths papers/v66s0906.pdf >> (full text available here) with the half-lives, peak times, animal self-administration, human/liking, actual abuse, withdrawal, memory impairment, lethality, and overall abuse liability of essentially every hypnotic imaginable. Scroll to page 37 and you'll find the chart.
poster:halcyondaze
thread:724283
URL: http://www.dr-bob.org/babble/20070119/msgs/724440.html