Posted by blueberry1 on January 15, 2007, at 5:02:23
In reply to Can Someone Explain Providgil So many Different Re, posted by Phillipa on January 14, 2007, at 12:35:12
> Seems that a lot of people are going on providgil and liking it. Can someone in English simple English explain how this med works? Is it good with anxiety? Love and Thanks Phillipa
Yeah, at remedyfind I was surprised to see how many people like it. Just a few didn't. In the antidepressant category it is actually rated #1. Of all the antidepresants out there, that took me by surprise.
How does it work? Like most drugs, they really don't know. They think it is an alpha-1 agonist, which basically helps existing norepinephrine work better. But, alpha-1 antagonists do not block its effects totally. So something else is up. There is mention of effects on dopamine in certain parts of the brain. Mention of it stimulating glutamate release. Who knows.
I want to try provigil. The closest I've tried is its parent adrafinil, which metabolizes in the body partially to provigil. All I know is that when I take adrafinil I definitely get more energy on the first day with a brightening of mood later in the day. The effects seem to dwindle after that. I think provigil would be cleaner and more powerful. Whether adrafinil and provigil are similar or not I don't know. But I was surprised that while adrafinil energizes me, clears my mind, lets me focus and work, it also cuts the edge off anxiety at the same time. Weird for a stimulant. But nice. The thing I don't like is that after a few days I get a sense of inner tension, inner restlessness, but it's not anxiety. Something different. Maybe I need xanax with it.
I'm in a real bad way waiting for my doctor appointment on Wednesday which seems like an eternity, as all I can think about is either dying or going to the hospital. Both losing propositions. So I guess I have to pull my trusty adrafinil out of the drawer to help me through a couple days.
Some people at rememdyfind say provigil is good for anxiety and some people say it worsens it. Like everything else, mileage varies.
poster:blueberry1
thread:722202
URL: http://www.dr-bob.org/babble/20070113/msgs/722436.html